pancreatic fibrosis

Regulation of Angiotensin ⅱ on Cell Apoptosis during the Development of Rat Pancreatic Fibrosis

血管紧张素Ⅱ对大鼠胰腺纤维化过程中细胞凋亡的调节作用

A mechanism study of sophorcarpidine in treatment of pancreatic fibrosis

苦参碱抗大鼠胰腺纤维化作用及机制研究

Expression of angiotensin II receptors after pancreatic fibrosis in rats

血管紧张素Ⅱ受体在胰腺纤维化大鼠胰腺组织中的表达及其意义

Inhibition of pancreatic fibrosis by angiotensin II type I receptor antagonist in rats

1型血管紧张素Ⅱ受体拮抗剂抑制大鼠胰腺纤维化形成

Roles of nuclear factor - κ B in the development of rat pancreatic fibrosis mediated by angiotensin II

核因子-κB在血管紧张素II介导的大鼠胰腺纤维化发生中的作用

Activated PSCs have been identified as an important cellular source of ECM in pancreatic fibrosis .

活化的PSCs是胰腺纤维化过程中胶原产生的重要来源。

TGF ‐β 3has anti ‐ fibrotic effect on liver fibrosis and pancreatic fibrosis .

同时，TGF-β3具有抗肝纤维化和胰腺纤化的功能。

Pancreatic fibrosis was induced by injection of 2 % TNBS into biliopancreatic duct .

大鼠胰管内逆行注射2%三硝基苯磺酸（TNBS）复制胰腺纤维化模型。

Pancreatic fibrosis Objective : To investigate the role of glutamine on apoptosis of pancreatic acinus in SAP rats .

目的：研究谷氨酰胺（Gln）对重症急性胰腺炎（SAP）大鼠胰腺细胞凋亡的影响。

In conclusion , oxidative stress , activation of PSCs and cytokines are the important mechanisms of pancreatic fibrosis and they interact .

氧化应激、PSCs活化和细胞因子是胰腺纤维化的重要机制，三者之间存在交互作用。

Pancreatic fibrosis was induced by intraperitoneal injection with diethyldithiocarbamate ( DDC 750 mg / kg body weight ) in rats .

以腹腔注射DDC（750mg/kg体重）每周2次，共6周建立胰腺纤维化动物模型，治疗组于DDC注射后2周起每日腹腔注射苦参碱（100mg/kg体重），6周后处死动物。

Conclusions Angiotensin ⅱ is involved in TNBS-induced pancreatic fibrosis probably through AT_1 and AT_2-mediated pathways .

结论血管紧张素II可能通过AT1、AT2介导的途径参与了TNBS诱导的大鼠胰腺组织纤维化形成过程。

Conclusions Losartan alleviates TNBS-induced pancreatic fibrosis in rats , suggesting that rennin-angiotensin system might be one of the important contributors for formation of pancreatic fibrosis .

结论1型血管紧张素Ⅱ受体拮抗剂对TNBS诱导的大鼠胰腺纤维化形成具有抑制作用，表明肾素血管紧张素系统（RAS）在慢性胰腺炎胰腺纤维化的发生发展过程中起重要的介导调节作用。

Conclusion High expression of transforming growth factor - β 1 ( TGF - β 1 ) which caused metabolic disorder of ECM may be closely related to the occurrence and development of pancreatic fibrosis for chronic pancreatitis .

结论转化生长因子（TGF）β1持续性高表达造成的ECM代谢紊乱，可能是导致慢性胰腺炎胰腺纤维化发生、发展的重要因素。

Increasing evidences suggest that oxidative stress and lipid peroxidation have tight relation with pancreatic fibrosis . They not only induce pancreatic cell damage directly , but also can activate PSCs , so promote the fibrotic process .

越来越多的研究显示胰腺纤维化的发生发展与氧化应激、脂质过氧化等有关：氧化应激不仅能够直接导致胰腺细胞损伤，还能激活PSCs，加速纤维化进程。

PANCREATIC SCHISTOSOMIASIS Pancreatic fibrosis Objective : To study the growth and development of embryonic pancreatic anlagen transplantation .

目的：研究胚胎胰组织在同种异体内再生长发育的可能性，并根据不同胎龄、不同移植部位的移植胚胰生长状况，研究大鼠胚胰移植的适合胎龄和移植部位。

Faecal elastase-1 test is superior to faecal lipase test in the assessment of exocrine pancreatic function in cystic fibrosis

粪弹性蛋白酶-1检验对囊性纤维化病胰腺外分泌功能的评估作用优于粪脂肪酶检验

Research on pancreatic stellate cell activation and experimental pancreatic fibrosis

急性胰腺炎大鼠胰腺星形细胞激活与纤维化改变的研究

The Study of Pancreatic Stellate Cell in the Mechanism of Pancreatic Fibrosis and Intervention of Salvianolic Acid B

胰腺星状细胞在胰腺纤维化中的作用及丹酚酸B的干预阻断研究

Objective To investigate the expression of angiotensin ⅱ receptors in pancreatic tissue and to clarify their effects on development of pancreatic fibrosis in rats .

目的动态观察血管紧张素II受体在胰腺纤维化大鼠胰腺组织中的表达并探讨其可能意义。

Recent studies display that oxidative stress , pancreatic stellate cells ( PSCs ) and cytokines are involved in the pancreatic fibrosis .

近年来的研究发现氧化应激、胰腺星状细胞（Pancreaticstellatecells，PSCs）及多种细胞因子与胰腺纤维化密切相关。

Objective To clarify the effect of lipid peroxidation on activation of pancreatic stellate cells ( PSC ) and its role in the formation of pancreatic fibrosis .

目的研究脂质过氧化对胰腺星状细胞（Pancreaticstellatecells，PSC）活化的影响及其在胰腺纤维化形成中的作用。